tumor suppression

A wireless brain implant inhibits tumor growth in rats, overcoming many design flaws of current devices used to treat glioblastoma.

Scientists found that combining the notoriously flimsy anticancer protein p53 with a domain from a spider silk protein resulted in a more stable hybrid that’s more potent and easier for cells to synthesize.

A high-salt diet suppressed the growth of tumors in a mouse model of melanoma, apparently because of an interplay between the gut microbiome and natural killer cells.

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

Even when a clinical trial fails, some patients improve. What can researchers learn from these exceptional responders?

The same microRNAs can have opposing roles in cancer.

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

A panel of oncologists discusses cases of exceptional responders, or cancer patients whose tumors disappear after a brief period of chemotherapy.

Advances in genomics and cancer biology will alter the design of human cancer studies.

Researchers have pinpointed the region of a key cancer gene that’s involved in tumor suppression.