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Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Mean, Green, Antibody-producing Machines
Shelby Bradford, PhD | Dec 1, 2023 | 2 min read
A plant-based monoclonal antibody goes head-to-head with its commercial counterpart to target tumors in mice.
New Strategies for Cancer Immunotherapy
The Scientist | 2 min read
An expert panel will discuss the interplay between cancer and the immune system, and how researchers develop immunotherapies and other immune-supporting strategies against cancer.
Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers
Natalia Mesa, PhD | Jun 30, 2023 | 3 min read
A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.
Mutational Signature Indicates Risk of Kidney Cancer Recurrence
Holly Barker, PhD | Mar 1, 2023 | 2 min read
DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.
How Can Core Labs Help You Get Started with NGS?
The Scientist | 1 min read
Next-generation sequencing (NGS) core facility scientists and researchers new to NGS discuss their fruitful collaborations, highlighting how to receive expert help from genomics facilities.
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Opinion: Stopping the Cancer Cells that Thrive on Chemotherapy
Chengsheng Wu, David Cheresh, and Sara Weis; The Conversation | Jan 17, 2023 | 5 min read
Research into how pancreatic tumors adapt to stress could lead to a new treatment approach.
Supporting the Evolution of Liquid Biopsies
The Scientist Creative Services Team in collaboration with Twist Bioscience | 1 min read
Sequencing circulating tumor DNA (ctDNA) within liquid biopsies permits tumor identification and tracking.
Transmissible Tumors, 1909
Katherine Irving | Jan 2, 2023 | 2 min read
Pathologist Peyton Rous made a groundbreaking discovery in the early 20th century, but his work wasn’t widely recognized until more than 40 years later.
Hypertranscription by Tumors Is Linked to Poorer Cancer Outcomes: Study
Sophie Fessl, PhD | Dec 13, 2022 | 3 min read
The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist | 1 min read
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Phenotypic Variation in Cancer Cells Often Not Due to Mutations
Jef Akst | Oct 26, 2022 | 3 min read
Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests.
Identifying Biomarkers to Guide Cancer Immunotherapy
The Scientist | 2 min read
An expert panel will discuss the cutting-edge technologies they used to identify novel biomarkers that predict patient responses to immunotherapy.
Immune Cells Imitating Neurons Cause Pain in Mice with Tumors
Shafaq Zia | Oct 18, 2022 | 3 min read
Whether the finding of a novel mechanism for cancer-related pain can lead to better treatments for neuropathic pain in people remains to be seen.
Fungal DNA, Cells Found in Human Tumors
Catherine Offord | Sep 30, 2022 | 2 min read
It’s not clear whether, or how, the organisms might play a role in disease pathology.
Finding CAR T Cells in Solid Tumors at Single-Cell Resolution
The Scientist Creative Services Team in collaboration with Miltenyi Biotec | 1 min read
Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM).
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.