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Beyond Gravity: Immune-Mediated Liver Damage in Spaceflight
Beyond Gravity: Immune-Mediated Liver Damage in Spaceflight
In this webinar, Noah Allen will explore how spaceflight changes the way organs and systems function, focusing on immune-mediated liver damage.
Beyond Gravity: Immune-Mediated Liver Damage in Spaceflight
Beyond Gravity: Immune-Mediated Liver Damage in Spaceflight

In this webinar, Noah Allen will explore how spaceflight changes the way organs and systems function, focusing on immune-mediated liver damage.

In this webinar, Noah Allen will explore how spaceflight changes the way organs and systems function, focusing on immune-mediated liver damage.

liver disease

T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
A nine-banded armadillo walking on dry grass.
Leprosy Bacterium Rejuvenates Armadillos’ Livers
Alejandra Manjarrez, PhD | Nov 15, 2022 | 4 min read
Mycobacterium leprae appeared to reprogram the animals’ livers to a state partially resembling early development, resulting in healthy organ growth.
illustration of liver with veins in blue and arteries in red.
Ethanol-Making Microbe Tied to Nonalcoholic Fatty Liver Disease
Natalia Mesa, PhD | Oct 19, 2022 | 4 min read
A study adds to evidence linking gut bacteria to liver conditions in people who don’t drink excessive amounts of alcohol. 
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Ribbon diagram of the protein coat of an adeno-associated virus
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Christie Wilcox, PhD | Jul 25, 2022 | 2 min read
Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.
Liver glowing red underneath human torso
Mysterious Hepatitis Cases Reported in Young Children
Natalia Mesa, PhD | Apr 18, 2022 | 3 min read
Officials have ruled out known hepatitis viruses as the cause of a rash of illnesses in Europe and the US.
LabTalk Podcast - The Promise of Spatial Transcriptomics in Exploring Chronic Liver Disease
The Scientist and 10x Genomics | Jun 30, 2021 | 1 min read
Prakash Ramachandran discusses using spatial transcriptomics to understand liver fibrosis and what he can learn from analyzing biobanked tissue samples.
Rotonya Carr, University of Pennsylvania, Perelman School of Medicine, underrepresented minority researchers, funding, academic medical centers, COVID-19, pandemic, SARS-CoV-2
Q&A: Unique Circumstances for Minority Scientists During COVID-19
Asher Jones | Mar 10, 2021 | 7 min read
Investigators from underrepresented groups have borne the brunt of the disruption to science from the pandemic, according to an opinion piece that outlines ways in which institutions can lessen the damage.
Organoids Repair Bile Ducts
Abby Olena, PhD | Feb 18, 2021 | 4 min read
Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally.
a photo of glasses of beer
Alcohol-Related Deaths in US Doubled in Past Two Decades: Study
Emily Makowski | Jan 8, 2020 | 2 min read
White women had the highest increase in death rate.
Gut Microbe Linked to Nonalcoholic Fatty Liver Disease
Abby Olena, PhD | Sep 19, 2019 | 3 min read
Researchers find strains of the bacterium Klebsiella pneumoniae that produce high levels of alcohol in 60 percent of patients with the condition.
CRISPR Editing Heads Off Disease in Mouse Livers
Shawna Williams | Oct 9, 2018 | 2 min read
Separate proof-of-concept studies report success against two inherited diseases.
Allerganā€™s Buying Spree Rolls On
Bob Grant | Sep 21, 2016 | 2 min read
The Ireland-based pharma company makes a $1.7 billion offer to acquire Tobira Therapeutics, a US firm developing liver disease drugs.
Improving Gene Therapy with In Vivo Selection
Tanya Lewis | Jun 8, 2016 | 3 min read
Scientists have developed a way to selectively expand genetically modified hepatocytes in mice.
Triglyceride Clock
Abby Olena, PhD | Feb 10, 2014 | 2 min read
The timing of meals affects the levels of lipids in the livers of mice, according to a study.
Obesity-Cancer Link Detailed
Chris Palmer | Jun 26, 2013 | 3 min read
Obesity drives an alteration of the gut microbiome, leading to the secretion of metabolites associated with the development of liver cancer.
Synthetic Spirits
David Nutt | Jan 1, 2011 | 3 min read
Can we use science to reduce the harms of alcohol?
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