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glioblastoma

Mega Multiplexing for Exploring Diseased Tissues

Niki Spahich, PhD | Oct 16, 2023 | 4 min read

Researchers at KU Leuven specialize in performing a multiplex immunohistochemistry method that uses conventional antibodies and pathologist-driven data analysis.

Machine Learning for Predicting Glioblastoma Prognosis

Tanvir Khan, PhD | Oct 4, 2023 | 3 min read

Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.

Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution

The Scientist Staff | 1 min read

In this webinar, Matthias Brendel will discuss a new PET approached called scRadiotracing, which involves immunomagnetic cell sorting after in vivo radiotracer injection combined with 3D histology.

Medical illustration of brain cancer with a microscopic magnification of malignant cells dividing in the tumor microenvironment.

Capturing the Brain Tumor Microenvironment with Tissue Engineering

Deanna MacNeil, PhD | Aug 4, 2023 | 3 min read

Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.

Turning up the Heat on Brain Tumors

Aparna Nathan, PhD | Jul 17, 2023 | 3 min read

Oncolytic viruses can help glioblastoma respond to immunotherapy.

Building Cancer Models with Creative Collaborators

Deanna MacNeil, PhD | 1 min read

Jennifer Munson shares how teamwork and collaboration have fostered her research at the intersection of creativity and clinical discovery.

Semi-circle of colorful cancer awareness ribbons

Electric Fields Disrupt Cancer Cell Division

Danielle Gerhard, PhD | May 4, 2023 | 5 min read

A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.

A collection of images from previous neuroscience articles, including those of an octopus in a chamber, artistic renditions of a brain, brain scans, and an image of neural connections in vitro.

Our Favorite Neuroscience Stories of 2022

Dan Robitzski | Dec 28, 2022 | 4 min read

This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more.

Learn about innovations in tissue regeneration

Stem Cell Engineering for Tissue Regeneration

The Scientist | 1 min read

Innovative strategies drive stem cell repair of organ damage.

This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022

Caught on Camera

The Scientist | Dec 12, 2022 | 4 min read

See some of the coolest images recently featured by The Scientist.

outline of a brain slice with white patch surrounded by teal

Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study

Patience Asanga | Oct 5, 2022 | 3 min read

Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.

The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity

The Scientist | 1 min read

Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.

black-and-white brain scan showing tumor

Glioblastoma Cells Imitate Immature Neurons to Invade the Brain

Sophie Fessl, PhD | Aug 5, 2022 | 3 min read

Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.

A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer

Roni Dengler, PhD | Sep 10, 2021 | 2 min read

A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.

Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57

Lisa Winter | Jul 28, 2020 | 3 min read

The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.

Zika as Cancer Buster?

Amy Schleunes | Apr 1, 2020 | 2 min read

By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.

CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity

Amy Schleunes | Mar 24, 2020 | 5 min read

A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.