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Infographic: Engineering Microbiomes with CRISPR
Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.
Infographic: Engineering Microbiomes with CRISPR
Infographic: Engineering Microbiomes with CRISPR

Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.

Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.

genetic engineering

A Virus that Generates Electricity 
Andrew Chapman | Nov 17, 2023 | 3 min read
Melting a bacteriophage’s coat of proteins turns it into a tiny power plant, which could fire up the discovery of new bioengineered devices.
Patient with skin blisters being swabbed by gloved hand
Delivering Gene Therapies in Utero 
Natalia Mesa, PhD | Jul 18, 2023 | 3 min read
By delivering mRNA to the skin of mice in utero, researchers showed a proof-of-concept for shuttling gene therapies to skin cells before birth.
iStock
Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering
The Scientist | 1 min read
Filippo Rossignoli discusses the challenges he faced when employing lentiviruses to produce immunotherapies and how he overcame these obstacles.
Black and white portrait of Paul Berg
‘Godfather of Genetic Engineering’ Paul Berg Dies at 96
Lisa Winter | Mar 23, 2023 | 3 min read
Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 for his work with recombinant DNA technology. 
Dead shark on concrete
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Natalia Mesa, PhD | Feb 22, 2023 | 3 min read
Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.
Sino Biological 
CAR Technology in Cancer Therapy: From CAR-T to CAR-NK
The Scientist and Sino Biological | 4 min read
From early target discovery to preclinical development stages, researchers explore novel strategies for effective cell therapies in cancer treatment.
The giant virus <em >Pandoravirus neocaledonia&nbsp;</em>inside the amoeba <em>Acanthamoeba castellanii</em>.
Giant Viruses Grew Out of Small Ones: Study
Kamal Nahas, PhD | Feb 13, 2023 | 4 min read
A study employing CRISPR/Cas9 to explore the evolutionary beginnings of some giant viruses finds evidence their large genomes arose from gene duplications.
illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Natalia Mesa, PhD | Dec 16, 2022 | 5 min read
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
Building Bridges podcast logo
Building Bridges for Translational Research - A Special Podcast Series
The Scientist and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
Lock and key illustration
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
Mosquito on leaf stock photo
Combating Mosquito-Borne Diseases with CRISPR
Niki Spahich, PhD | Oct 11, 2022 | 4 min read
As alternatives to insecticides, Omar Akbari uses sophisticated genetic engineering methods to solve the world’s mosquito problems.
Molecular Farming: The Future of Pharmaceuticals
The Scientist Speaks - Molecular Farming: The Future of Pharmaceuticals
Niki Spahich, PhD | 1 min read
Julian Ma discusses past, present, and future uses of plant biotechnology for disease treatments.
an artistic rendering of CRISPR/Cas9
Ten Years of CRISPR
Sophie Fessl, PhD | Jun 28, 2022 | 7 min read
This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.
Illustration of blue shiny mitochondria
Worms Live Longer with Mitochondria Powered by Light: Preprint
Alejandra Manjarrez, PhD | May 24, 2022 | 4 min read
Increasing mitochondrial activity in worms by engineering a light-activated proton pump into the organelle’s membrane extends the animals’ lifespan without evidence of health decline, according to a preprint.
Repurposing a Pathogenic Bacteria’s Weapon
LabTalk Podcast - Bugs with Drugs: Repurposing a Pathogenic Bacteria’s Weapon
The Scientist | 1 min read
Cammie Lesser describes her research developing designer probiotics to deliver protein-based therapeutics to the gut.
An orange CRISPR Cas 9 enzyme cutting DNA
CRISPR-Based Treatment Successfully Lowers Toxic Protein Levels
Natalia Mesa, PhD | Mar 2, 2022 | 3 min read
A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.
Histological stain of motor neurons in purple and green
Researchers Use Ultrasound to Control Neurons in Mice
Natalia Mesa, PhD | Feb 9, 2022 | 4 min read
A study shows “sonogenetics” could be a useful new tool in neuroscience and other fields.
Abstract geometric heart with plexus effect on blue background
Man Receives Transplanted Heart from Genetically Modified Pig
Shawna Williams | Jan 10, 2022 | 3 min read
The procedure, performed last Friday, is a milestone in a long effort to boost the number of organs available for safe transplantation.
rice plants growing in a room with metal walls under artificial light
Rice-based Cholera Vaccine Induces Antibodies in Small Trial
Alejandra Manjarrez, PhD | Jul 8, 2021 | 4 min read
Immune-response levels to the edible vaccine varied among the subjects, possibly due to differences in the gut microbiome.
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