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Black and white portrait of Paul Berg
‘Godfather of Genetic Engineering’ Paul Berg Dies at 96
Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 for his work with recombinant DNA technology. 
‘Godfather of Genetic Engineering’ Paul Berg Dies at 96
‘Godfather of Genetic Engineering’ Paul Berg Dies at 96

Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 for his work with recombinant DNA technology. 

Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 for his work with recombinant DNA technology. 

enzymes

Two pink-colored, rod-shaped bacteria interacting with a blue-colored human cell
Gut Bacterium Linked to Depression in Premenopause
Alejandra Manjarrez, PhD | Mar 17, 2023 | 2 min read
The opportunistic pathogen Klebsiella aerogenes degrades estradiol and induces depressive-like behavior in mice, a study finds.
Pseudomonas aeruginosa biofilm
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Katherine Irving | Jan 26, 2023 | 3 min read
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Enzymes Cutting Extracellular Matrix
An Introduction to Enzymes
The Scientist | 1 min read
Discover how enzymes work and why they're an integral part of scientific laboratories.
Tree with many scattered branches.
Scientists Resurrect Ancient Rubiscos to Understand Their Evolution
Alejandra Manjarrez, PhD | Oct 14, 2022 | 5 min read
A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2.
LAKSAMEE CAVE
Clinton Cave Investigates How Brain Cells Communicate
Andy Carstens | Sep 1, 2022 | 3 min read
The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.
ELISA tips and tricks
Technique Talk: ELISA Tips and Tricks
The Scientist | 1 min read
Learn to optimize ELISA experiments in this workshop.
Artist’s 3D rendering of malignant cancer cells, illustrated in pink, as it would appear under a scanning electron microscope.
Underdog Enzyme Likely Responsible for Mutations in Most Cancers
Sophie Fessl, PhD | Jul 28, 2022 | 3 min read
A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.
3D illustration showing neurons inside the brain
Experimental Pill to Treat Parkinson’s Is Safe, Trial Finds
Andy Carstens | Jun 10, 2022 | 2 min read
Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.
Extreme Biotech: Understanding Extremophile Biology to Impact Human Health
The Scientist | 1 min read
Jaclyn Winter and Shiladitya DasSarma will discuss how they harness the unique biology of extremophiles for the discovery and development of new therapeutics.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 2 min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
A micrograph of the prion-like state of a protein called Pus4
Protein Mediates Non-Genetic Inheritance of Growth Strategies
Catherine Offord | Jan 4, 2022 | 2 min read
An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.
DNA
In Editing RNA, Researchers See Endless Possibilities
Christie Wilcox, PhD | Dec 1, 2021 | 10 min read
RNA editing has been in DNA editing’s shadow for nearly a decade, but recent investments in the technology could bring it into the limelight.
Photograph of a brown laboratory mouse
Experiment Gone Awry Suggests Novel Way to Combat Hypoxia
Phil Jaekl | Oct 1, 2021 | 4 min read
While exploring suspended animation in mice, scientists discover how an enzyme can protect the brain from dangerously low levels of oxygen.
Profile of old man wearing glasses, looking up to the left.
Edmond Fischer, Biochemist and Nobel Laureate, Dies at 101
Lisa Winter | Aug 31, 2021 | 2 min read
Fischer was recognized for his work with reversible protein phosphorylation.
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena, PhD | Aug 6, 2021 | 4 min read
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
Black and white image of Jean Wilson in an office, wearing a lab coat.
Endocrinologist Jean Wilson Dies at 88
Lisa Winter | Jun 24, 2021 | 2 min read
The University of Texas Southwestern professor’s research focused on the androgen hormones that cause male sexual differentiation and may also lead to prostate disease.
a white menstrual pad with pink and yellow spotting
Threads Embedded in Pads and Tampons Can Diagnose Yeast Infection
Emma Yasinski | Jun 15, 2021 | 3 min read
The material turns bright pink when it comes in contact with an enzyme produced by the fungus Candida albicans.
Infographic: Light Triggers Photocage Opening, Apoptosis Inhibition
Jef Akst | Jan 1, 2021 | 1 min read
Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.
Blood Transplants from Active Mice Give Brain Boost to Others
Lisa Winter | Jul 12, 2020 | 2 min read
The researchers behind the results propose that an exercise-induced protein in circulation is responsible for the benefits.
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