People have long associated being cold with getting sick. With the advent of germ theory, doctors and scientists began to suspect that it wasn’t the temperature itself making people fall ill, but rather that something about harsher conditions weakened the immune system, allowing viruses people are exposed to—such as those behind the common cold, the flu, or COVID-19—to take hold more easily. However, the precise reasons that chilly temperatures increase infection susceptibility has remained elusive, so seasonality is usually explained by changing human behavior patterns—especially a tendency to crowd together indoors to escape colder weather.
Now, research published today (December 6) in The Journal of Allergy and Clinical Immunology offers up a mechanism that could explain how being cold influences catching a cold: Nasal cell defenses are weaker when the cells are cold. “Conventionally, it was thought that cold and flu season occurred in cooler months because people are stuck ...





















