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Illustration of a web of dark blue neurons with a purple glow at the center of each neuron.
How the Brain Hits the Brakes on Aging 
Neurons linked to metabolic processes slow aging in mice.
How the Brain Hits the Brakes on Aging 
How the Brain Hits the Brakes on Aging 

Neurons linked to metabolic processes slow aging in mice.

Neurons linked to metabolic processes slow aging in mice.

News & Opinion

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
3D outline of a bone with red dots in the center.
Bringing Immunotherapy Straight to the Source
Aparna Nathan, PhD | Mar 14, 2024 | 4 min read
Engineered natural killer cells track down cancer cells in the bone marrow.
3D illustration of a lymphocyte in white and green.
A Quest for the Holy Grail of Cancer Targets
Danielle Gerhard, PhD | Mar 14, 2024 | 5 min read
Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.
The mitochondria inside of a neuron are shown in red. The neuron’s protrusions called dendritic spines are shown in cyan.
How Mitochondria Stay Still in Neurons
Mariella Bodemeier Loayza Careaga, PhD | Mar 13, 2024 | 5 min read
An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 
High magnification image highlighting small hairlike projections called cilia, which help the biobots move.
A Leap Towards Building Synthetic Organisms 
Laura Tran, PhD | Mar 12, 2024 | 6 min read
Douglas Blackiston’s frog-fueled research seeks to push the boundaries of understanding developing organisms.
A blue background with colorful illustrated viral particles
Delivering Prime Editors With Virus-like Particles
Deanna MacNeil, PhD | Mar 11, 2024 | 3 min read
An iterative engineering approach to improve prime editor delivery helped scientists correct genetic vision defects in mice.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes. 
Stepping Into the Unknome
Danielle Gerhard, PhD | Mar 8, 2024 | 5 min read
A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.
A computer-generated brain encapsulated in an ice cube rests on a table
How Cold Affects the Brain
Andrew Chapman | Mar 7, 2024 | 4 min read
The brain works hard to keep the body warm in cold weather, but a drop in core temperature can cause troublesome chemical changes.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Stay Salty: Maternal Diet Affects an Offspring’s Neuronal Taste Circuit
Shelby Bradford, PhD | Mar 6, 2024 | 3 min read
Low salt intake during pregnancy in mice influences the pruning of extra synapses of the taste circuit later in life.
Two Neuron Populations Prolong Aggression
Holly Barker, PhD | Mar 4, 2024 | 4 min read
Scientists are a step closer to uncovering the neural changes that underlie sustained mental states.
Electric Bacteria: Out of the Darkness and into the Light
Hannah Thomasy, PhD | Feb 29, 2024 | 6 min read
Once obscure mud microbes inspire a new generation of living electronics.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Oxidation Signals Tardigrades to Enter Hibernation
Aparna Nathan, PhD | Feb 27, 2024 | 4 min read
Water bears survive some of Earth’s harshest conditions by relying on their own chemical alarms.
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Macrophages on the Fast Track to Tumor Defense
Laura Tran, PhD | Feb 22, 2024 | 3 min read
In a race to the tumor, a macrophage’s phenotype can give it a leg up on the competition.
A Signal for T Cells to Remember
Patience Asanga | Feb 22, 2024 | 3 min read
Timely modulation of a common signaling pathway can preserve influenza memory in lung T cells.
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