immunology

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Flickr, Marcel van Schooten

Rural Teens Have Fewer Allergies

By Megan Scudellari

The diversity of microbes in the great outdoors may protect against inflammatory disorders.

PLAYING OFFENSE: T cells, like the one pictured here, do not attack cancer cells when in the presence of certain signals. New research shows that what was thought to be a suppressive signal may actually help activate an anticancer immune attack. NIAID

Tumor Turnabout

By Megan Scudellari

A cytokine involved in suppressing the immune system may activate it to kill cancer cells.

NO COLUMN REQUIRED: Exposing monoclonal antibodies to multivalent haptens produces high-molecular-weight complexes that can be easily processed by precipitation. Basar Bilgiçer (center), who developed the technique, gives a demonstration of its simplicity to graduate students Nathan Alves (left) and Michael Handlogten (right) in his lab at the University of Notre Dame.Wes Evard, College of Engineering, University of Notre Dame

Pure Pursuits

By Katherine Bagley

Techniques for simpler, cheaper, and better antibody purification

S. aureus bacteria being attacked by human white blood cells.NIAID/RML

Anti-inflammatory Factors Fight Bugs

By Megan Scudellari

A combination of antibiotics and the body’s own defensive metabolites clears bacterial infections faster than antibiotics alone.

Rhesus macaqueWikimedia Commons, Yann

Social Rank Affects Monkey Immunity

By Megan Scudellari

In rhesus macaques, an individual’s drop in the social hierarchy leads to overactive immune genes and, possibly, poor health.

Healthy workers of the invasive garden ant (Lasius neglectus) remove the infectious fungal pathogen (Metarhizium anisopliae) from an exposed individual (colour marked by a red dot). Matthias Konrad, IST Austria

Ants Share Pathogens for Immunity

By Sabrina Richards

A new study shows that grooming by ants promotes colony-wide resistance to fungal infections by transferring small amounts of pathogen to nestmates.

An array of microneedles can be coated with medicine and act as a painless drug delivery system for vaccinesEmory University

Next Generation: Painless Vaccine Patch

By Megan Scudellari

Vaccination via tiny microneedles elicits a powerful immune response in the skin.

Flickr, David K.

Let Them Eat Dirt

By Megan Scudellari

Early exposure to microbes shapes the mammalian immune system by subduing inflammatory T cells.

Microglia (green) and neurons (red). Wikimedia Commons, Gerry Shaw/Encor Biotech

Immune Role in Brain Disorder?

By Hannah Waters

Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.

Organ transplantationWikimedia commons, Espa1010

Transplant Without Drugs?

By Edyta Zielinska

A new method for transplanting immunologically mismatched organs may remove the need for life-long immunosuppressive drugs to prevent rejection.

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