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Identifying Diet-Treatable Diseases

By Sabrina Richards

Scientists test which mutations underlie metabolic diseases that may benefit from changes in diet.

Lung cancer cell with irregular bulges in the plasma membrane (purple)Flickr, Wellcome Images

News from Cancer Meeting

By Cristina Luiggi

A roundup of recent research announced this week at the annual conference of the American Association for Cancer Research (AACR).

Wikimedia Commons, Fir0002/Flagstaffotos

Lab Studies Lie about the Clock

By Megan Scudellari

Fly circadian behavior is dramatically different in natural environments than in the lab.

A. Petrosiute, J. Myers, A. Huang

Eyes on Cancer

By Amber Dance

Techniques for watching tumors do their thing

Photo Researchers, Inc., David McCarthy

Are Cancer Stem Cells Ready
for Prime Time?

By Suling Liu, Hasan Korkaya, and Max S. Wicha

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.

PICK A COLOR: Each tube shows the fluorescence of a mixture of a specific RNA and a synthetic fluorophore whose structure is based on the fluorescent moiety of GFP. Samie Jaffrey and JEremy Paige, Cornell University

Live and In Color

By Sarah Webb

How to track RNA in living cells

Ahna Skop: Associate Professor of Genetics and Medical Genetics, University of Wisconsin–MadisonUniversity of Wisconsin-Madison, Jeff Miller

Truth and Beauty

By Karen Hopkin

With strong foundations in both art and science, Ahna Skop has been able to capture the marvel of—and mechanisms behind—cytokinesis.

INTEGRIN TRAP: Rab25 proteins bind integrins in the cell membrane and shuttle them to lysosomes. If the Rab25 shuttles the integrins to a lysosome where CLIC3 is absent, then they are degraded (A). If CLIC3 is present on the surface of the lysosome, the integrins survive and are shuttled to the rear of the cell where they help the cell detach from the extracellular matrix (ECM) and become metastatic (B). Precision Graphics

A Malignant Alliance

By Megan Scudellari

Two proteins interact to save adhesion molecules from degradation, potentially contributing to a more aggressive cancer.

Detail of a Wenzel Hollar drawing Wikimedia Commons, University of Toronto Wenceslaus Hollar Digital Collection

Baldness Genes Discovered?

By Bob Grant

Researchers say they’ve found key molecular clues to a problem that plagues 80 percent of men.

Flickr, kyz

Debate over RNA Transcription

By Edyta Zielinska

Researchers question earlier findings of a new mechanism for gene regulation.

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