Vaccines
Looking back, looking ahead
By Robin A. Weiss and Peter HaleJune 2011
Table of Contents
Cover Story
Features
The Last Vaccine Frontier
By Brad SpellbergSuccessful vaccines have been created to protect against pathogenic bacteria and viruses. Why aren’t there any for combating fungal infections?
Recognizing the Human Potential
By Gene M. Shearer and Adriano BoassoIt may be time to reconsider an AIDS vaccine which is more human than viral, triggering the immune system in a way that no other vaccine does.
Departments
Editorial
A Shot in the Arm
By Edyta ZielinskaDecades of vaccine research have expanded our understanding
of the immune system and are yielding novel disease-fighting tactics.
Notebook
Summit Science
By Alison SnyderResearchers seeking a link between vision problems and the dangerous physiological effects of hypoxia in mountain climbers are taking their work to new heights.
One Bad Apple
By Richard P. GrantA unique virus and the worm it infects turn up in an orchard outside of Paris.
Simultaneity
By Cristina LuiggiTwo research teams studying a rare genetic disorder discover independently that it’s caused by genes that are crucial to DNA replication.
Cellular Salve
By Cristina LuiggiIvan Martin talks about the promise of using cell-based therapies to regenerate joint cartilage.
Speaking of Science
Speaking of Science
June 2011′s selection of notable quotes
Thought Experiment
First, Do No Harm…
By Jim WoodgettIs DNA damage an inevitable consequence of epigenetic reprogramming?
Critic At Large
Hard and Harder
By Michael K. GusmanoThe path to eradicating malaria in Africa involves much more than just a vaccine.
The Literature
Approaching Universality
By Rino RappuoliPitfalls and triumphs on the way to complete vaccine protection.
Hiding Under a Cap
By Richard P. GrantEditor’s Choice in Immunology
The Axis of Aging
By Hannah WatersEditor’s Choice in Developmental Biology
A Joint Endeavor
By Hannah WatersEditor’s Choice in Physiology
Reading Frames
The Gravity of Life
By Rob DunnWhose well-being is threatened by our changing relationship with the myriad organisms that shaped the evolution of our species?
Scientist to Watch
Dominique Bergmann: Probing Plant Pores
By Jef AkstAssistant Professor, Department of Biology, Stanford University. Age: 41
Lab Tools
Track Your Package
By Amber DanceHow to follow stem cells transplanted into living tissue.
Bio Business
Take Two of These
By Bob GrantDrugmakers are teaming up to test the disease-fighting power of combination therapies earlier in the development cycle than ever before.
Capsule Reviews
Capsule Reviews
By Richard P. GrantThe Evolutionary World, The Darwin Archipelago, Dream Life, Boffinology
Foundations
One-Man NIH, 1887
By Cristina LuiggiAs epidemics swept across the United States in the 19th century, the US government recognized the pressing need for a…
Contributors
Contributors
Meet some of the people featured in the June 2011 issue of The Scientist.
