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Jon Krause

Shooting Down Addiction

By Thomas Kosten | June 1, 2011

A new breed of vaccines aims to wean users off cocaine.

Kevin Hand

Power Failure

By Megan Scudellari | May 1, 2011

Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?

Sean Mccabe

Wrestling with Recurrent Infections

By Gayatri Vedantam and Glenn S. Tillotson | May 1, 2011

Clostridium difficile is evolving more robust toxicity, repeatedly attacking its victims, and driving the search for alternative therapies to fight the infection.

4x6 | istockphoto.com

Best Places to Work Industry, 2011

By Hannah Waters | May 1, 2011

By forging new relationships and finding novel uses for existing technologies, this year’s top companies are employing creative ways to advance their science.

3-D reconstruction of confocal images showing membrane tubes pulled from a giant unilamellar vesicle by kinesin motors along microtubules. The tube diameter is about 100 nm and the vesicle diameter about 15 μm. Courtesy of Cécile Leduc

The Movement of Goods Around the Cell

By Patricia Bassereau and Bruno Goud | April 1, 2011

A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells.

Pep Karsten / fstop / Corbis

Taking Aim at Melanoma

By Keith T. Flaherty | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.

Colin Anderson / Gettyimages

An Aspirin for your Cancer?

By Giorgio Trinchieri | April 1, 2011

Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?

moredun animal health ltd/spl/gettyimages

Epigenetic Changes in Cancer

By Manel Esteller | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

Infographic: Epigenetics: A Primer View full size JPG | PDF  illustration ©2011 Tolpa Studios, Inc.

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.

Jasper James / Gettyimages

Environmental Impact

By David Berreby | March 1, 2011

Research in behavioral epigenetics is seeking evidence
that links experience to biochemistry to gene expression
and back out again.