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Elaine R. Mardis, Codirector, Director of Technology Development at The Genome Institute, Washington University School of MedicineBarlow Productions, Bill Sawalich

High-Tech Choir Master

By Karen Hopkin | January 1, 2012

Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.

Joshua R. Sanes, Professor of Molecular and Cellular Biology, Paul J. Finnegan Family Director, Center for Brain Science, Harvard University PORTER GIFFORD

Critical Connections

By Karen Hopkin | December 1, 2011

Through a series of sustained collaborations, Joshua Sanes has deciphered the molecular synergy that guides synapse formation.

Philippa Marrack: Investigator, Howard Hughes Medical Institute Professor, Integrated Department of Immunology, National Jewish Health, Denver, Colorado; Distinguished Professor, University of Colorado Health Sciences Center David X. Tejada

Beyond Expectation

By Karen Hopkin | September 1, 2011

Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.

Nadrian C. (Ned) Seeman: Margaret and Herman Sokol Professor of Chemistry, New York UniversityMichael Summers

3-D Seer

By Karen Hopkin | August 1, 2011

Dissatisfied with the uncertainty of crystallography, Ned Seeman invented a new way of assembling the molecules that encompass the logic of life.

Carla Shatz: Sapp Family Provostial Professor Director, Bio-X Program Professor of Biology & Neurobiology Stanford UniversityGREGORY COWLEY

Foresight

By Karen Hopkin | July 1, 2011

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.

H. RONALD KABACK Professor of Physiology University of California, Los Angeles F1000 Faculty Member: Neuronal Signaling Mechanisms Photo © 2011 Jim Cornfield

Making the Gradient

By Karen Hopkin | May 25, 2011

Ron Kaback didn’t believe that electrochemical gradients could power the transport of sugars and amino acids across cell membranes—until he proved that they do.

JOY WARDAssociate Professor of Plant Physiological Ecology and Global Change, University of Kansas F1000 Faculty Member, Physiological Ecology Jason Dailey

Harvesting Ideas

By Karen Hopkin | April 1, 2011

Joy Ward is reaping the rewards of her studies on how plants handle global climate change—gathering academic accolades and presidential embraces along the way.

RUDOLF JAENISCH Professor of Biology, MIT Member, Whitehead Institute F1000 Head of Faculty, Genomics & Genetics Porter Gifford

Ready, Reset, Go

By Karen Hopkin | March 1, 2011

Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.

LEWIS C. CANTLEY Professor of Systems Biology, Harvard Medical School Chief, Division of Signal Transduction, Director of Cancer Research Beth Israel Deaconess Medical CenterPorter Gifford

Impure Genius

By Karen Hopkin | February 1, 2011

Lewis Cantley has made a career of turning chemical contaminants into groundbreaking discoveries—including novel lipids, potent inhibitors, and kinases involved in cancer.

Fiona Watt: Deputy Director, Wellcome Trust Centre for Stem Cell Research; Herchel Smith Professor of Molecular Genetics, University of Cambridge; Deputy Director, Cancer Research UK, Cambridge Research Institute.Alex Rumford

Watt Fun!

By Karen Hopkin | January 1, 2011

Her doctoral advisor told her to amuse herself, and Fiona Watt has done just that—probing individual stem cells and determining the genes and molecules that direct them to differentiate or cause them to contribute to cancer.