Modus Operandi

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05_12_MO_F

Bubble Vision

By Edyta Zielinska | May 1, 2012

Turning a liability into an asset, cryo-electron microscopists exploit an artifact to probe protein structure.

04_12_Brighter-BeaconC

A Brighter Beacon

By Edyta Zielinska | April 1, 2012

A novel liquid laser set-up can detect single nucleotide mutations in a cancer gene.

03_12_ModOpC

Delivering Silence

By Sabrina Richards | March 1, 2012

Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.

02_12_Switching-the-Bait

Switching the Bait

By Edyta Zielinska | February 1, 2012

Turning a standard technique into an unbiased screen for diagnostic biomarkers

01_12_ModOpF

It’s Easy Being Green

By Richard P. Grant | January 1, 2012

Now RNA can glow in the cell, as only proteins could in the past.

12_11_ModusOp

Flow Cytometry for the Masses

By Richard P. Grant | December 1, 2011

Tagging antibodies with rare earth metals instead of fluorescent molecules turns a veteran technique into a high-throughput powerhouse.

09_11_modusOperandi

Deep Tissue Treatment

By Tia Ghose | September 1, 2011

A new, genetically encoded tag for electron microscopy may revolutionize studies of specific proteins in cells and tissues.

Infographic by George Retseck

The Right Sort

By Richard P. Grant | August 1, 2011

Using the strongest molecular binding partnership in biology to separate different cell types

Infographic: Smashing Crystals View full size JPG | PDF | View video Infographic by George Retseck

Smashing Crystals

By Richard P. Grant | July 1, 2011

A powerful new X-ray–generating laser is imaging smaller crystals than ever before.